2025-07-05
On June 27, 2025, China's National Medical Products Administration (NMPA) announced the approval of Innovent Biologics' application for the launch of the glucagon/glucagon-like peptide-1 (GCG/GLP-1) dual receptor agonist Mazdutide injection. Mazdutide is a GLP-1 drug developed by Innovent Biologics, which, unlike semaglutide and tirpatide, targets glucagon-like peptide-1 (GLP-1) receptors and glucagon (GCG) receptors. Activation of GLP-1 receptors, which can suppress appetite and delay gastric emptying, thereby reducing food intake; Activation of GCG receptors can promote liver lipolysis and enhance energy expenditure, thereby improving fatty liver.